Antimicrobial resistance surveillance of gram-negative bacteria among solid organ transplant recipients, a 4-year retrospective study

This study examines the resistance-susceptibility patterns of gram-negative bacteria in patients undergoing solid organ transplantation at Shiraz Transplant Center. The study retrieved 2075 GNB isolates from patients, with E.coli, Klebsiella, Pseudomonas, Acinetobacter, Enterobacter, Citrobacter, and Stenotrophomonas maltophilia being the most common. The majority of the isolates were liver transplant recipients, with carbapenem-resistant Enterobacterales, particularly K. pneumoniae, showing an increasing pattern of resistance towards carbapenems, particularly in liver transplant recipients. Understanding these patterns is crucial for antibiotic stewardship programs.